Journal of JCIC

Online edition: ISSN 2432–2342
JCIC学会事務局 JCIC学会事務局
〒162-0801東京都新宿区山吹町358-5アカデミーセンター Academy Center, 358-5 Yamabuki-cho, Shinju-ku, Tokyo 162-0801, Japan
Journal of JCIC 10(2): 31-35 (2026)
doi:10.20599/jjcic.10.31

症例報告症例報告

Gore Cardioform ASD Occluder留置後に生じた可逆性II度房室ブロックReversible second-degree atrioventricular block after transcatheter closure of ASD using a Gore Cardioform ASD Occluder

1埼玉県立小児医療センター循環器科Department of Pediatric Cardioligy, Saitama Prefectural Children’s Medical Center ◇ Saitama, Japan

2東京慈恵会医科大学小児科Department of Pediatrics, the Jikei University School of Medicine ◇ Tokyo, Japan

受付日:2026年1月9日Received: January 9, 2026
受理日:2026年4月13日Accepted: April 13, 2026
発行日:2026年7月31日Published: July 31, 2026
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心房中隔欠損症(atrial septal defect: ASD)に対する閉鎖栓であるGore® Cardioform ASD Occluder(GCA; W. L. Gore & Associates, Inc., Flagstaff, AZ, USA)は柔軟性が高くErosionが少ないとされるが,房室ブロックはまれに報告されている.症例は13歳女性.欠損孔18 mmのASDで,心房中隔長は44 mmであった.大動脈rimの一部が欠損し,上方のrimが乏しかったため,GCA 44 mmを選択した.展開直後よりI度房室ブロックが出現し,一時的にWenckebach型II度房室ブロックへ進展したが,ステロイド内服投与で10日後には改善した.房室ブロックの発生機序として,本症例では心房中隔長に対して大きな閉鎖栓を使用したことにより心房中隔が広範囲に覆われ,機械的圧迫を生じたことが原因となった可能性がある.一方,ステロイド治療開始後に房室ブロックの改善を認めたことから,可逆的な炎症性浮腫などの要因の関与も示唆された.GCAでも条件や閉鎖栓の選択によっては房室ブロックを生じ得るが,抜去は慎重に判断し,ステロイド治療を含めた保存的治療も考慮する余地がある.

The Gore® Cardioform ASD Occluder (GCA) is a flexible device with a low incidence of erosion. However, atrioventricular (AV) block has occasionally been reported when using the GCA. Here, we report the case of a 13-year-old girl with atrial septal defect (ASD). An ASD defect measuring 18 mm, a deficient aortic rim, and poor superior rim were observed. The atrial septal length was 44 mm. We selected a 44 mm GCA because of the deficient aortic rim and poor superior rim. After the device was deployed, a first-degree AV block occurred, which temporarily progressed to a Wenckebach-type second-degree AV block. However, the conduction disturbance improved within 10 days after initiation of oral steroid therapy. In this case, using a large-sized device relative to the septal length provided wide coverage of the atrial septum, and mechanical compression was thought to be the cause of the AV block. On the other hand, improvement in the AV block after the initiation of steroid therapy suggests that reversible factors, such as inflammatory edema, may also have been involved. Although an AV block may occur with the GCA depending on the anatomical conditions and device selection, the decision to retrieve the device should be made with caution, and conservative management, including steroid therapy, may be considered.

Key words: atrial septal defect; transcatheter closure; Gore Cardioform ASD Occluder; atrioventricular block

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