Journal of JPIC

Online edition: ISSN 2432–2342
JPIC学会事務局 JPIC学会事務局
〒162-0801東京都新宿区山吹町358-5アカデミーセンター Academy Center, 358-5 Yamabuki-cho, Shinju-ku, Tokyo 162-0801, Japan
Journal of JPIC 4(1): 1-5 (2019)

症例報告Case Report

動脈管開存症に対するAmplatzer™ Vascular Plug II(AVPII)を用いた閉鎖術デバイス選択と留置手技の考察Transcatheter closure using Amplatzer™ Vascular Plug II (AVPII) for patent ductus arteriosusConsideration of device selection and deployment methods

公益財団法人日本心臓血圧研究振興会附属榊原記念病院小児科Department of Pediatric Cardiology, Sakakibara Heart Institute ◇ Tokyo, Japan

受付日:2019年2月19日Received: February 19, 2019
受理日:2019年5月7日Accepted: May 7, 2019
発行日:2019年8月31日Published: August 31, 2019

背景:Amplatzer™ Duct Occluder-I(ADO I)では閉鎖困難と想定される形態の動脈管に対して,海外ではAmplatzer™ vascular plug II(AVPII)を用いた閉鎖術が報告されている.しかし,本邦における報告は少なくAVPIIのサイズ選択や留置方法,中長期的な安全性について一定の見解はない.



結果:症例1はKrichenko分類C型,肺動脈側3.7 mm,長径18.8 mmの動脈管に対して,まずAVPII10 mm,次にAVPII14 mmの留置を試みたが,いずれも良好な留置形態を得られず回収.最終的にAVPII12 mmを留置した.症例2はKrichenko分類E型,肺動脈側6.1 mm,長径17.0 mmの動脈管に対して,まずAVPII12 mmの留置を試みたが,軽いwiggle testで肺動脈内に脱落したため回収.最終的にAVPII16 mmを留置した.変更の要因は閉鎖栓とPDAの径のミスマッチによる不安定性と留置後の閉鎖栓の長さと動脈管長のミスマッチの2点に要約された.特に留置後の閉鎖栓の長さが治療の成否に重要であるが変化の幅は大きい.本検討から留置後閉鎖栓の長さはカタログ上の閉鎖栓の径×長さを管状動脈管径で除した数値で予測できると考案した.


Background: Transcatheter closure of patent ductus arteriosus (TC-PDA) using Amplatzer™ vascular plug II (AVPII) have been reported overseas in the case where Amplatzer™ Duct Occluder-I (ADO I) does not fit. However, there have been few reports in Japan, especially device selection and deployment methods.

Purpose: To develop a method for device selection and deployment in TC-PDA using AVPII.

Object and Methods: We retrospectively examined the deployment of AVPII with 5 different sizes in 2 patients who underwent TC-PDA using AVPII in our hospital and examined the appropriate AVPII selection and deployment methods according to PDA size and shape.

Results: Case1 had PDA of Krichenko type C with PA side diameter of 3.7 mm and length of 18.8 mm. We attempted to place AVPII10 mm at first, and then AVPII14 mm, however both did not fit in PDA and were retrieved. Finally we successfully deployed AVPII12 mm. Case2 had PDA of Krichenko type E with PA side diameter of 6.1 mm and length of 17.0 mm, we attempted to place AVPII12 mm at first, the device was migrated into the pulmonary artery with a light wiggle test and was retrieved. Finally we successfully deployed AVPII16 mm. The factors of exchange were summarized in two points, the instability due to the mismatch of the diameter of the PDA and device as well as the length of PDA and device after deployment. From this study, we developed the simple method in that the length of device after deployment can be predicted by the diameter×length of device on the catalog divided by the diameter of the tubular PDA.

Conclusion: AVPII can be safely used for long tubular PDA, which is considered to be a good indication. Regarding the selection of the device size, an algorithm is required to comprehensively determine the minimum diameter of the device in relation to the PDA diameter and predict device length after deployment.

Key words: Patent ductus arteriosus; Amplatzer™ vascular plug II; Transcatheter closure

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